Posted August 21, 2008. 3 I dont know what FDG avid means or that maximum stuff Of the numerous additional lung nodules evident by CT, at least 3 in the left lower lobe and one each in the posterior right upper lobe and along the left heart border. Although 18 F-FDG-avid ovarian lesions in postmenopausal women are considered suspicious for malignancy,. These PET scans use a substance, called a radiotracer, to highlight areas of activity within the body that are suggestive of cancer. 4). Numerous primary bone tumors are encountered on 18F-FDG PET/CT, and many are FDG avid. The mean PSA level for all patients in the benign group was 2. OBJECTIVE. Differential considerations include that of either an inflama. 4), is shown to be undescended at the time of imaging, situated adjacent to the deep inguinal. The SUVs of various organs were determined from the transverse views. This review will illustrate the spectrum of nodal. Thus, the combination of the information from the PET and CT scans must be used in these patients to differentiate radiation pneumonitis from recurrent tumor. 5 cm solitary nodule with ground glass borders that highly suspicious for Bronchioloalveolar carcinoma and warranted furt. It stands for Fluorodeoxyglucose. Q: Is melanoma FDG-avid? A: Yes, it is probably the most FDG-avid tumor cell type. The mean standardized uptake value for the area of spinal involvement is 11. This pictorial essay discusses breast lesions that show increased FDG activity, mimicking breast cancer, with biopsy-confirmed benign diagnosis. No bulky or FDG avid adenopathy. The mean SUVmax was 6. The endometrium and ovaries may demonstrate physiologic FDG avidity. FDG-avid on PET Low probability ~5-15% or less Intermediate Probability High Probability >60%. The mean SUVmax of MM (1. Our aim was to explore the tumor metabolism in 2 populations of. However, lack of anatomic landmarks, variable physiologic uptake, and asymmetric FDG distribution in several altered physiologic states can. had respiratory symptoms and fever on admission and COVID-19 was not confirmed by RT. 19 Most studies evaluating its accuracy have relied on a visual assessment. Case One - Staging FDG-PET/CT demonstrates intense FDG-avidity (SUVmax 19) in a bulky and heterogeneous retroperitoneal mass [orange arrows] (a1–3, b1–2). An SUV value is one of the many ways to follow the scan, it’s not an absolute way to look at what the results mean. The idea is that FDG is taken up more in abnormal tissues then normal ones. avidity. Unexplained focal FDG accumulation in the abdomen is sometimes noted, but the clinical significance of this finding is unknown. Lymphoma, leukemia, and metastatic disease can involve the kidney. FDGuptakeifPET-FDGstudiesneedtoberepeatedat differentbloodglucoselevels. Intratumoral fat can be either macroscopic fat (i. PET–computed tomography (CT) can be useful in. Of those 122 patients, 55 (45%) had abnormal cutaneous or subcutaneous up-take, 95 (78%) had FDG-avid lymphadenop-athy, and 54 (44%) had FDG-avid extranod-The ipsilateral axillary lymphadenopathy was the most FDG-avid in the first two weeks post vaccination, with a mean SUV max value of 3. , those discovered during imaging of a patient with a nonbreast malignancy) have a 30–40% chance of being malignant [16, 17] . It is a simple way to determine how much activity or FDG uptake there is on a PET scan in the tissues. If the disorder it is reacting to is rapidly progressive, there may only be time for retreat (defense). The gallbladder (GB) is not usually visualized as an 18 F-fluorodeoxyglucose (18 F-FDG)-avid structure in routine clinical positron emission tomography/computed tomography (PET/CT) studies, unless affected by an inflammatory or neoplastic process [1, 2]. Explanations for improved reader certainty with PET. Neuroendocrine tumors can demonstrate the flip-flop phenomenon, in which FDG fluorine 18 fluorodeoxyglucose uptake is inversely correlated with 111 In pentetreotide uptake. 17. The investigation of solitary pulmonary nodule (SPN) and non-small cell lung cancer (NSCLC) has rapidly become one of the main indications for. FDG uptake exceeding liver FDG uptake) bone lesions is still unknown. 5 is used as the cutoff, but this choice was never deduced from respective studies. What does high SUV max mean? The rationale for using FDG-PET in oncology is its ability to measure increased glucose metabolism of tumor cells. FDG meaning: 1. Fluoro-2-deoxy-D-glucose-positron emission tomography (FDG-PET) is utilized in more than 90% of cancers in staging, re-staging, assessing therapy response and during the follow-up. Positron emission tomography (PET) with 2-[fluorine-18] fluoro-2-deoxy-d-glucose (FDG) has been effective for the diagnosis, staging, and restaging of malignancies of the head and neck region. Most FDG-avid lymph nodes were of normal size (mean, 0. Numerous primary bone tumors are encountered on 18F-FDG PET/CT, and many are FDG avid. 5% of patients imaged for staging or response assessment of malignancy and represents thyroid cancer in approximately 35% of cases. As with FDG uptake,. 016). A few points need to be considered before understanding FDG. read moreOf significance, in 13 patients with 2-[fluorine-18]fluoro-2-deoxy-D-glucose (FDG)-avid splenic lesions, four had normal CT findings. (B) Axial PET, CT, and fused PET/CT. Benign or malignant etiology. THE FULL ARTICLE TITLE: Beech P et al. 2%). What does low grade FDG avid mean?In patients with a known primary breast malignancy, an FDG-avid breast soft-tissue lesion is, of course, likely the known primary malignancy. To conduct a literature review of FDG uptake in benign sinonasal papillomas. The FDG-avid distal esophageal wall thickening represents the known primary esophageal malignancy. Every year, nearly two million PET scans are performed on patients to check for. As part of the lymphadenopathy work-up, many patients undergo [ 18 F]FDG-PET/CT for purposes of ruling out malignancy. Maximum standardized uptake value (SUVmax) of the benign lymph nodes ranged from 2. Receiver. myelodysplastic syndromes. Results. PET-avid HCA are. if it’s “glucose avid” or not. High levels of calcium in the blood (hypercalcemia), which can cause nausea, vomiting, constipation and confusion. This is because of physiologic excretion of FDG through the kidneys, ureters, and bladder. up was changed in four cases after FDG PET. 18F-FDG PET is the most accurate noninvasive modality for staging mediastinal lymph nodes in lung cancer. Patients undergoing 2-[fluorine 18]fluoro-2-deoxy-d-glucose (FDG) whole-body oncologic positron emission tomography (PET)/computed tomography (CT) are studied while fasting. Of the 136 FDG-avid sdLNs, 16% (22/136) sdLNs were enlarged. 5 y; 260 females) with PTC referred for the first RIT and who underwent routine preablative FDG PET between April 2011 and February 2013. FDG-positive lesions often mean cancer, but not always. This can lead to a lump or mass of atypical tissue that can harm or destroy the healthy tissue and also weaken the bone. 4 ± 0. Focal FDG tracer accumulation due to cancer, however, must be distinguished from normal, normal variant, and benign pathological sources of FDG uptake. Therefore, we followed cases with unexplained. The radiation. 17. The most widely used pharmaceutical is the radiolabeled glucose analog fluorine-18-deoxyglucose (FDG). There are many causes of osseous FDG avidity that are benign and must be distinguished from. Prominent increased large bowel uptake is generally seen in. Bone lesions can sometimes press on nerves and cause pain. 48 The impact of FDG PET/CT on systemic staging may be lower for ILC patients than for IDC patients. FDG is a radioactive analog of glucose and follows the initial steps of glucose transport and phosphorylation. The cyst-like non FDG-avid lesion in the left side of the uterus represented a leiomyoma (G, bold arrow; H, bold arrow). 4, which was described by radiologist as "intense". 2. 1) was significantly less than that for bone metastasis (5. (FDG) PET/CT is an imaging modality for cancer diagnosis, staging of patients with newly diagnosed. A radioactive substance is given to the patient and this attaches to glucose, which is attracted to cells that are hypermetabolic. Larger lymph nodes with mild 2-[ 18 F]FDG uptake, some with fatty hilum and/or unsuspicious pattern on CT, were categorized as reactive or. maximum standardized uptake value 8. It does not have therapeutic use. FDG is the radioactive tracer used in PET Scans. Surgical pathology of left seminal membranous muscle revealed presence of hibernoma. FIG. The maximum Standard Uptake Value (SUVmax) obtained using F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) is the best non-invasive technique available for this evaluation, but its performance varies from center to center. 001). The aim of the present study is to enlarge the growing body of evidence concerning 18F-FDG avidity of lymphoma to provide a basis for future guidelines. Positron emission tomography with the radiotracer 18 F-fluoro-2-deoxy-d-glucose (FDG) plays an important role in the evaluation of bone pathology. 1. The urinary tract is one the most difficult organ systems of the body to evaluate on F18-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT). What does avid mean on a PET scan? Positron emission tomography (PET) using [18F] fluorodeoxyglucose (FDG) is commonly used in cancer staging, surveillance and evaluation of treatment response. Learn more. FDG Avid in simple words means metabolically active malignant lesions. The ratio of men to women was 1. A straight-line sign has been reported in diffuse peritoneal carcinomatosis [2], mak-ing peritoneal involvement more apparent on FDG PET/CT than on CT alone (Fig. 3 ) and unfortunately may be. FDG-PET/CT is now routinely used in the head and neck for the delineation of the primary. carcinomas are poorly avid for FDG. See how your treatment is working. The FDG-avid periaortic node is a thoracic nodal metastasis. Among them, we included only cases with sonography studies and cytology results from FNAB. Brain 18F-FDG PET allows the in vivo study of cerebral glucose metabolism, reflecting neuronal and synaptic activity. Mostly, an SUV of 2. Distant metastases from breast cancer most frequently occur in the skeleton. A new FDG-avid nodule was noted in the left lower lobe (panel B and C) which due to respiratory movement appeared ill-defined. Throughout the last several decades, 18F-FDG, a glucose. It is important to understand the normal patterns of cardiac FDG activity that can be seen. e. 18 F-FDG; PET/CT; pulmonary nodule; lung metastasis; PET with 18 F-FDG is widely used for the staging and restaging of various malignancies, such as lung cancer, esophageal cancer, colorectal cancer, lymphoma, melanoma, breast cancer, and head and neck cancers (1,2). I hope I can explain this to you. (A) FDG maximum intensity projection (MIP) demonstrates FDG avidity in the region of the bilateral adrenal glands (arrows) . No other abnormal FDG-avid foci were identified. 1 (range 2. SUVmax of the malignant lymph nodes ranged from 2. Many potential pitfalls and artefacts have been described in PET imaging that uses F-18 fluorodeoxyglucose (FDG). Abstract. Low PSMA expression or discordant FDG-avid disease in patients with mCRPC who progress after conventional therapies identifies a group with poor prognosis and short survival. OBJECTIVE. Just got a PET scan on my oncologist request and was looking at the report. Whether their report says ‘no FDG uptake,’ ‘abnormal FDG uptake,’ ‘low grade. A variety of adverse effects from chemotherapy, targeted therapy, immunotherapy, and radiation therapy are. [] found a high sensitivity (29/31 lesions [94%]) of FDG PET for detecting hepatic metastases. e. FDG PET is frequently used as part of the diagnostic workup in cancer patients. This review article discusses mechanisms of 18 F-FDG uptake in tumors in contrast to infection and inflammation with examples of infectious and inflammatory pitfalls in oncologic 18 F-FDG PET/CT imaging and interpretation. We performed a retrospective study of patients with enlarged mediastinal lymph nodes on F-FDG PET/CT scans. Download figure; Open in new tab;FDG uptake refers to the amount of radiotracer uptake. Among the analyzed factors including sex, age, tumor size, cause of cirrhosis, AFP, PIVKA, differentiation, Child-Pugh class, death from HCC. 9. Depending on what's causing the condition, symptoms also might include: Diarrhea. Abstract. Fluorine 18 fluorodeoxyglucose (FDG) is a readily available radiotracer that offers rapid, exquisitely sensitive high-resolution tomography. Describe tumors likely to show low FDG avidity. Consequently, the 2015 American Thyroid Association guidelines strongly recommend investigation of all 18F-FDG–avid nodules 1. 2. First, not all cancer cells use the same amount of glucose: some use more and some use less. 9 ± 2. Ultrasound stratification of the FDG-avid thyroid nodule. 0 – 17. 6 and 4. Whole-body [18F]-fluorodeoxyglucose (FDG) PET/CT and segmental PET/MRI of the left hip. Methods One hundred forty-five consecutive retrospective. "Favored to be reactive" means that from their appearance on the scan, they appear more likely to be enlarged because they are fighting an infection rather. 1 C], axial fused [Fig. 5 or greater has been used to differentiate between benign and malignant nodules. Consequently, the 2015 American Thyroid Association guidelines strongly recommend investigation of all 18 F-FDG-avid nodules 1 cm or larger. Focal 18 F-fluorodeoxyglucose (FDG) colonic activity can be incidentally seen in positron emission tomography/computed tomography (PET/CT) scans. What does 'avid' mean? "FDG avid" is a term primarily used by radiologists to describe sturctures in PET scans which have taken up and concentrated fluorodeoxyglucose more than surrounding tissues. granulocyte colony-stimulating factor (G-CSF) post-chemotherapy. CHEST: Pulmonary nodules less than 10 mm in maximum dimension are often below PET resolution. 01, Table 1 ). Mechanism of uptake and metabolism of 18 F-FDG. First and foremost, most FDG PET/CT scans are. Recently, studies of 18 FDG-PET/CT showed 18 FDG-avid ground-glass opacities, consolidative opacities and lymph nodes in patients with clinical suspicion of COVID-19. What is FDG-avid mass? FDG-avid primary breast tumors have favored first spread to the lung and liver, which suggests that tumor cells with heightened glycolytic activity better colonize these organs. 36 (1. FDG-avid lymph nodes (FALNs) were identified using retrospective image reviews. Understand the importance of including low FDG uptake tumors in differential diagnosis. A variety of lesions have increased FDG radiotracer including infection, inflammation, autoimmune. (h) Diagnostic MDCT at the corresponding site of right rib FDG activity shows no cortical destruction or well defined lytic lesion. 5% of patients imaged for staging or response assessment of malignancy and represents thyroid cancer in approximately 35% of cases. We do have a definition for this sense of avid (“desirous to the point of greed”), and it is the oldest meaning of the word, dating in use to the middle of the 17th century. Conversely, complete resolution of FDG uptake in a treated lesion does not necessarily indicate absence of viable cells. 1 and 2). Visualization of radiotracer-avid foci suggests the presence of malignant disease. Lytic lesion leads to holes in the body parts making the bone. In our study only 22/281 nodes which underwent USgFNAC where FDG-negative, none. Highly FDG-avid lesions would be the lesions to target for evaluation of possible high-grade malignancy. 26. FDG is a glucose analog consumed by both malignant and inflammatory lesions. FDG avidity in the neck that corresponds to fat on the CT is almost certainly benign brown fat. e. FDG (b MIP and fused images): increased tracer uptake in the IV segment (CT images red arrow) is consistent with the primary HCC The main clinical application of 11 C-acetate is the detection of non 18 F-FDG-avid neoplasm, such as differentiated hepatocellular carcinoma and renal cell carcinomas (Hain and Maisey 2003 ; Ho et al. These entities can be differentiated from. 2 and 3). Many lesions tend to occur in a “favorite” part of the bone. erythropoietin. This article provides an update on the current methods and applications of imaging techniques for detecting and characterizing bone metastases, with a focus on the advantages and limitations of each modality. To learn more about our services, call Independent Imaging at (561) 795-5558 to request an appointment, or use our online request an appointment form. 8) in FDG-avid group. The noun 'children' is a commonnoun, the plural form of the noun child. Histopathology results in 35 patients revealed tuberculosis in 12, sarcoidosis in 8, and lymphoma in 15. Fluorodeoxyglucose (FDG) PET/CT is a vital imaging technique used for staging, assessing treatment response, and restaging following completion of therapy in patients who are undergoing or have completed oncologic treatment. 1 E], and coronal CT [Fig. i had a mastsectomy last year and also a pelvic mass removed in a hysterectomy last. 5 ± 3. You’ll have a CT scan with a low dose of radiation at the same time as your PET scan. There is no one definitive meaning for “fdg avid meaning. An SUV cutoff of 2. PET-avid HCA are rare and. Does FDG uptake indicate the presence of cancer? [Dr. Location. Values are presented as the mean ± standard deviation for data that were normally distributed or the median and. Abstract. FDG-PET staging in head and neck cancer has good positive and negative predictive values in determining lymph node status. In fact, accurate staging at diagnosis is imperative to prevent. What does low grade FDG avid mean? In patients with a known primary breast malignancy, an FDG-avid breast soft-tissue lesion is, of course, likely the known primary malignancy. So, if any of you know what any of this means, let me know. FDG-avid sdLNs in preoperative PET/CT. Since cancer cells are more active than normal cells, the cancer cells take up more of the radiolabeled glucose and show up on the FDG-PET scan. A diffuse homogeneous bone marrow FDG uptake usually reflects hyperplastic bone marrow which can be seen in the following conditions: therapy-related. The average mean and maximum standardized uptake values (SUVs) are 0. However, one of the most important challenges is to correctly differentiate the abnormal uptake that. 1 D], coronal PET [Fig. The favored locations are listed in the figure below. 2, no other abnormal uptake was observed elsewhere in the body. Clin Radiol 2016;71:164-9. 26. 2. Yet, at times there is associated FDG activity. progressive disease (PD): a Deauville score of 4 to 5 with increasing intensity compared to baseline or any interim scan and/or any new FDG-avid focus consistent with malignant lymphoma 7. As part of the lymphadenopathy work-up, many patients. The mean sensitivity of a CT scan is 73% for detecting primary tumor and 80% and 75% for hepatic and extrahepatic metastases, respectively . 5, 3. There are many FDG-avid lung lesions which will be determined to be benign or malignant only after correlation with CT findings and the clinical history. FDG is a radioactive sugar that is used in PET imaging. A wide variety of pulmonary infections can be 18 F-FDG-avid, including typical and atypical organisms such as bacterial, fungal, TB, nocardia, and pneumocystis [6•, 7,8,9]. An FDG-avid lesion in the sternum on the axial images is suspicious for an osseous metastasis (arrows). On rare occasions, they can become large enough to press on nearby organs. Having knowledge of the physiological uptake of 18F. Abstract Body: Summary: The use of FDG PET in oncology has led to the identification of a number of malignancies. 9 x 6. 4 to 34 with a mean±SD of 10. The vast majority. 1. It stands for Fluorodeoxyglucose. Non-FDG avid 3 mm right middle lobe pulmonary nodule, lung image 47. FDG-PET/CT cannot substitute for biopsy in determining the malignancy of a breast lesion. FIG. This is the first study evaluating the use of both 18 F-FDG uptake patterns and CT margins of focal parotid lesions on PET/CT for differentiating benign from malignant parotid lesions. stable disease (SD), also called no metabolic response: a Deauville score of 4 or 5 without significant change in FDG uptake from baseline. This is a principal task in the interpretation of whole-body FDG PET scans applied to oncologic diagnosis. The visceral pleura covers each lung surface, and the parietal pleura covers the inner surface of the thoracic cavity. 7% vs. 9, and 2. on FDG PET images. No FDG-avid. What does avid mean on a PET scan? Positron emission tomography (PET) using [18F] fluorodeoxyglucose (FDG) is commonly used in cancer staging, surveillance and evaluation of treatment response. SUV on PET scan means standard uptake value. Learning Objectives: 1. Figure 12c. FDG is a glucose analog consumed by both malignant and inflammatory lesions. Interpretation requires integration of the metabolic and anatomic findings provided by the PET and CT components which. 15 (SD) and 0. Lymph nodes. 1 C], axial fused [Fig. Incidental non-pathologic 18 F-FDG activity within the GB has been described in the. Few faint FDG avid nodes (retroperitoneal, with the largest measuring ~ 1. Figure 5a. 3 to 11. The FDG PET and/or CT scan was performed for staging and further evaluation and it displayed avidity of the nodule with a standardized uptake value (SUV). What do these SUV values mean, and is a higher number an. 001). Axial PET, CT, and fused PET/CT images through three levels of the brain. What does FDG avid mean? An FDG avid node means a node which is taking up a lot of the glucose used in PET scans. When used in the sentence FDG avid , it means that the nodes or tumors takes up the FGD, also known as Hot nodes. The highest reported mean SUVmax in the physiological focal F-FDG uptake was 2. Despite its. 8 with a mean±standard deviation (SD) of 5. CT scans take a fast series of x-ray pictures. 74, respectively of FDG PET for the detection of VPGI. In terms of oncologic applications, FDG PET has already. Normally the liver has a dual blood supply. Although PET/CT is not routinely recommended for the evaluation of incurable lymphoma, including non-FDG avid or variably FDG-avid lymphoma subtypes , CTCL and CBCL typically are FDG avid on PET/CT [93, 96–98]. The standardized uptake value (SUV) applies to PET imaging of tumors and typically uses the radioligand F 18-2-fluoro-2-deoxy-D-glucose (FDG). Hence, in. There is a 1. While PET imaging demonstrating avid FDG uptake is associated with an increased risk of. (A) Axial PET, CT, and fused PET/CT through the pancreas in a patient with pancreatic adenocarcinoma demonstrate focal FDG avidity in the pancreatic tail, probably representing a known pancreatic adenocarcinoma (arrows) . 6 x 1. FDG is a radioactive sugar that is used in PET imaging. Introduction. (B) More inferior slice demonstrates that the basal ganglia (arrowhead) are often the most FDG-avid normal. This energy is detected by the PET scanner creating images showing how your tissues and organs are. Sheikh] For many patients who get an FDG PET scan, their number one question is in relation to understanding what FDG uptake means. MATERIALS AND METHODS. The tremendous variability in physiologic FDG avidity in the head and neck may make distinguishing FDG-avid malignancy from benign physiologic FDG avidity difficult. liver reference FDG uptake to determine the D5PS score (Fig. On the other side an avid and corrupt conscience is over at war within. We evaluated the efficiency of FDG PET/CT for the differentiation of malignant from benign mediastinal masses and neurogenic tumors of chest-wall. Its clinical significance is still unclear. As part of the lymphadenopathy work-up, many patients undergo [ 18 F]FDG-PET/CT for purposes of ruling out malignancy. Cancer cells with a faster metabolic rate such as colorectal adenocarcinoma are very FDG avid, whereas others such as mucinous cancers consume less glucose and therefore are less FDG avid. (60%–70% of cases), and papulonodular skin lesions appear at a mean of 3 years after arthritis . Accounting for 4% of pelvic NHL, 16 the mean age is 60, often presenting with a nodule, induration, a mass in the region of Bartholin’s gland or a clitoral mass. Your physician will discuss these results with you and explain what they mean in. The FDG PET and/or CT scan (trans-axial CT [Fig. Results: We report the case of a 69-year-old man presenting with an isolated left maxillary sinus mass with avid FDG uptake, discovered on PET/CT imaging. In most other cases, comparison with prior studies and/or additional imaging can afford an accurate diagnosis. Loss of appetite. Fever. The radioactive substance most commonly used in PET scanning is a simple sugar (like glucose) called FDG, which stands for “fluorodeoxyglucose”. Normally, the visceral and parietal pleura oppose each other, have negligible material. But. Examination: PET scan skull base to midthigh. Hepatocellular adenoma (HCA) is the second most common benign liver neoplasm and occurs predominantly in women in their reproductive years. Liver cancer does not cause symptoms in its early stages. 1 C], axial fused [Fig. A collective noun is a word used to group people or things taken together as one whole in a descriptive way. 2. Semi-quantitative standardized uptake value (SUV) is known to be affected by multiple factors and may fail. Focal FDG tracer accumulation due to cancer, however, must be distinguished from normal, normal variant, and benign pathological sources of FDG uptake. 6, Deauville score of 3. If the maxSUV was between 0 and 2. 1 F]) was performed for staging and further evaluation, and it revealed an FDG-avid nodule with an SUV of 6. 2 adjacent masslike areas in the lower lobe the right lung which are FDG avid. Keywords: breast cancer, FDG, hormone receptor, metastatic site, PET/CT. Heterogeneous patchy marrow uptake on FDG PET in a histologically proven case of lymphoma is usually considered a. Metastatic RCC is often intensely FDG-avid and can be associated with FDG-avid tumor thrombus in the inferior vena cava . It is important for the radiologist to be aware of benign and malignant. At its core, the intracellular concentration of FDG can be described as a function of its. Fluorodeoxyglucose (FDG) has proven benefits as a positron emission tomography (PET) radiopharmaceutical in oncology. Malignant tumors with high glucose metabolism show preferential uptake of FDG than normal cells. INTRODUCTION. Fatigue. 5 is often used as a cut off value for. Our research aimed to explore an effective diagnostic model that combined 18 F-FDG PET/CT imaging findings and clinical factors to assess BM in GC. Identify reasons for low FDG uptake in known malignancies. What does PET avid mean? Positron emission tomography (PET) using [18F] fluorodeoxyglucose (FDG) is commonly used in cancer staging, surveillance and evaluation of treatment response. 64 ± 4. 2, no other abnormal uptake was observed elsewhere in the body. A healthy 49-year-old nonsmoker lady, who was found to have an incidental finding of a lung lesion on a chest X-ray. Keywords: breast cancer, FDG, hormone receptor, metastatic site, PET/CT. 17. Positron emission tomography/computed tomography (PET/CT) is currently one of the main imaging modalities for cancer patients worldwide. When interpreting a PET scan, one should be aware of the histopathological sub-type and, if mucoid, then one should clearly state on the report that there is a high probability ofDiscussion. Positron emission tomography (PET) is a diagnostic imaging technique that allows identification of biochemical and physiologic alterations in tumors. 3) were analyzed. Consequently, the 2015 American Thyroid Association guidelines strongly recommend investigation of all 18F-FDG–avid nodules 1 cm or larger with ultrasound and fine-needle aspiration cytology. 3 to 11. 5). Imaging of the visualized portion of the head and neck is unremarkable and shows no discrete abnormal FDG activity to suggest FDG-avid malignant process. Lai et al. Fluorodeoxyglucose (FDG) PET/CT has earned its global recognition in the modern management of cancer patients and is rapidly becoming an important imaging modality for patients with cardiac, neurological, and infectious/inflammatory conditions.